What We Do

Where Syndx fits

Explore how SynDx supports both clinical trials and frontline psychiatric care — through the same standardized neurophysiology pipeline.

Clinical Decision Support

SynDx transforms raw EEG into an interpretable brain report to support differential diagnosis and treatment planning for MDD and ADHD.

Objective neurophysiology for modern psychiatry.

Clinical Workflow

  1. 1

    EEG Acquisition

    Resting-state EEG recorded in clinic or partner lab.

  2. 2

    Preprocessing

    Automated artifact cleaning and signal normalization.

  3. 3

    Biomarker Extraction

    EEG biomarker computation including TBR, IAPF, and wPLI connectivity metrics.

  4. 4

    Connectivity Graph

    wPLI-based functional connectivity network construction.

  5. 5

    Hybrid AI Fusion

    Neuro-symbolic model outputs diagnostic probability.

  6. 6

    Clinician Report

    PDF & portal report with actionable interpretation.

What the Doctor Receives

SynDx ReportID: SYN-4829-A

Diagnosis Probability

MDD72%
ADHD28%

Key Biomarkers

4.8Theta/Beta Ratio
-0.23Frontal Alpha Asym.
0.61Frontal Theta Cordance
Connectivity Abnormality67%

Clinical Notes

Elevated TBR with left-lateralized frontal alpha asymmetry suggests attentional and affective comorbidity. Recommend follow-up PLI analysis.

Report Deliverables

  • Differential diagnosis support
  • Biomarker summary report
  • Connectivity signature indicators
  • Suggested follow-up flags
  • Longitudinal tracking across visits

Biomarker Indicators

72

TBR

Theta/Beta Ratio

Attention dysfunction marker — elevated in ADHD profiles.

58

FAA

Frontal Alpha Asymmetry

Emotional regulation — lateralized patterns linked to MDD.

61

Cordance

Frontal Theta Cordance

Cerebral perfusion proxy — treatment response predictor.

45

IAPF

Inter Alpha Peak Frequency

Dominant frequency within the brain’s alpha wave band, linked to cognitive efficiency and alertness.

67

wPLI

Weighted Phase Lag Index

Functional connectivity strength — graph-level brain network.

Why It Matters

Before SynDx

  • Subjective clinical interview
  • Diagnostic uncertainty
  • Trial-and-error medication
  • Patient disengagement

With SynDx

  • Objective EEG-based report
  • Quantified biomarker evidence
  • Data-driven treatment confidence
  • Improved patient retention

Clinically Validated

84%Accuracy

TDBRAIN dataset · n > 1,200+ sessions

Hybrid neuro-symbolic pipeline (biomarkers + connectivity).

SynDx is a decision-support tool intended to complement DSM-based assessment and clinician expertise.

Join Clinical Network

Equip your practice with SynDx neurophysiology tools. Now accepting partners for our clinical beta program.